Biological embedding of childhood maltreatment in adult depression
MC Jawahar, BT Baune - Inflammation and Immunity in Depression, 2018 - Elsevier
Childhood maltreatment (CM) has been shown to increase the risk for adult
psychopathology and attributes to 23% of depression cases. Depression is a
multidimensional syndrome leading to increased morbidity and mortality with significant
economic and social disease burden. The early experience-dependent shaping of the
neuroendocrine-immune systems in response to CM termed as biological embedding is
reviewed here with relevance to adult depression. Our findings suggest that exposure to CM …
psychopathology and attributes to 23% of depression cases. Depression is a
multidimensional syndrome leading to increased morbidity and mortality with significant
economic and social disease burden. The early experience-dependent shaping of the
neuroendocrine-immune systems in response to CM termed as biological embedding is
reviewed here with relevance to adult depression. Our findings suggest that exposure to CM …
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