Bivalirudin as compared to unfractionated heparin in patients undergoing percutaneous coronary revascularization: A meta-analysis of 22 randomized trials
M Verdoia, A Schaffer, L Barbieri, H Suryapranata… - Thrombosis …, 2015 - Elsevier
Bivalirudin has gained ground against unfractionated heparin (UFH) in percutaneous
coronary interventions (PCI), due to a reported better safety profile. However, whether
bivalirudin may provide also advantages in clinical outcome beyond the known benefits in
major bleedings, is still a debated matter and was, therefore, the aim of present meta-
analysis of randomized trials, evaluating efficacy and safety of bivalirudin as compared with
UFH in PCI. Methods and study outcomes Literature archives (Pubmed, EMBASE …
coronary interventions (PCI), due to a reported better safety profile. However, whether
bivalirudin may provide also advantages in clinical outcome beyond the known benefits in
major bleedings, is still a debated matter and was, therefore, the aim of present meta-
analysis of randomized trials, evaluating efficacy and safety of bivalirudin as compared with
UFH in PCI. Methods and study outcomes Literature archives (Pubmed, EMBASE …
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