There is concern that climate change will lead to expansion of vector-borne diseases as, of all disease types, they are the most sensitive to climate drivers. Such expansion may threaten human health, and food security via effects on animal and crop health. Here we quantify the potential impact of climate change on a vector-borne disease of livestock, bluetongue, which has emerged in northern Europe in response to climate change^{, –}, affecting tens of thousands of farms at huge financial cost and causing the deaths of millions of animals. We derive future disease risk trends for northern Europe, and use a detailed spatial transmission model to simulate outbreaks in England and Wales under future climatic conditions, using an ensemble of five downscaled general circulation models. By 2100, bluetongue risk extends further north, the transmission season lengthens by up to three months and outbreaks are larger on average. A 1 in 20-year outbreak at present-day temperatures becomes typical by the 2070s under the highest greenhouse gas emission scenario. However, animal movement restrictions are sufficient to prevent truly devastating outbreaks. Disease transmission uncertainty dominates over climate uncertainty, even at the longest prediction timescales. Our results suggest that efficient detection and control measures to limit the spread of vector-borne diseases will be increasingly vital in future, warmer climates.