Burn Wound Healing Activity of Ethanolic Extract of Acalypha indica in Oinment Formulated against Rabbits (Ocyctagus caniculus)

K Fitri, TN Khairani, FA Sinaga… - Asian Journal of …, 2020 - ajprd.com
Asian Journal of Pharmaceutical Research and Development, 2020ajprd.com
Objectives: The purpose of this study was to determine burn wound healing activity of
Acalypha indica L. in oinment formulated. Design: This study uses an experimental
laboratory design. This study used rabbits as test animals induced by burns with hot iron
plates on the back. Extract ointment applied to the wound then observed the development of
healing. Interventions: The extract was formulated in ointments with concentrations of 3, 5
and 7%. positive control used was ointment containing sesame oil and negative control …
Abstract
Objectives: The purpose of this study was to determine burn wound healing activity of Acalypha indica L. in oinment formulated.
Design: This study uses an experimental laboratory design. This study used rabbits as test animals induced by burns with hot iron plates on the back. Extract ointment applied to the wound then observed the development of healing.
Interventions: The extract was formulated in ointments with concentrations of 3, 5 and 7%. positive control used was ointment containing sesame oil and negative control used is an ointment base.
Main outcome measure: The results showed a concentration of 3% had a slow and low effect, at a concentration of 5% it had a moderate healing phase, and a concentration of 7% had a good healing phase.
Conclusion: The ointments containing Acalypha indica leaf extracts have good activity in healing burns in rabbits.
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