Buserelin inhibits apoptosis in male germ cells induced by busulfan in mouse testis

F Mohammad Ghasemi, MH Bahadori… - Anatomical Sciences …, 2009 - anatomyjournal.ir
Purpose: The aim of this study was to investigate the effect of buserelin on apoptosis of male
germ cells induced by busulfan in adult male mice. Materials and Methods: Male adult NMRI
mice were divided into four group of eight each. Group 1 (control) administered PBS for 21
days subcutaneously, group 2 given 0.4 mg buserelin for 21 days subcutaneously, group 3
given single dose of 30 mg/kg busulfan intraperitoneally and group 4 given both busulfan
and buserelin for 21 days. The animals were sacrificed and their testes were dissected 35 …

Buserelin inhibits apoptosis in male germ cells induced by busulfan in mouse testis

GF Mohammad, B MH, RJ Soleimani - 2009 - pesquisa.bvsalud.org
The aim of this study was to investigate the effect of buserelin on apoptosis of male germ
cells induced by busulfan in adult male mice. Male adult NMRI mice were divided into four
group of eight each. Group 1 [control] administered PBS for 21 days subcutaneously, group
2 given 0.4 micro g buserelin for 21 days subcutaneously, group 3 given single dose of 30
mg/kg busulfan intraperitoneally and group 4 given both busulfan and buserelin for 21 days.
The animals were sacrificed and their testes were dissected 35 days after the treatment …
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