COPLA, a taxonomic c lassifier of pla smids
S Redondo-Salvo, R Bartomeus-Peñalver, L Vielva… - BMC …, 2021 - Springer
Background Plasmids are mobile genetic elements, key in the dissemination of antibiotic
resistance, virulence determinants and other adaptive traits in bacteria. Obtaining a robust
method for plasmid classification is necessary to better understand the genetics and
epidemiology of many pathogens. Until now, plasmid classification systems focused on
specific traits, which limited their precision and universality. The definition of plasmid
taxonomic units (PTUs), based on average nucleotide identity metrics, allows the generation …
resistance, virulence determinants and other adaptive traits in bacteria. Obtaining a robust
method for plasmid classification is necessary to better understand the genetics and
epidemiology of many pathogens. Until now, plasmid classification systems focused on
specific traits, which limited their precision and universality. The definition of plasmid
taxonomic units (PTUs), based on average nucleotide identity metrics, allows the generation …
COPLA, a taxonomic classifier of plasmids
[Background]: Plasmids are mobile genetic elements, key in the dissemination of antibiotic
resistance, virulence determinants and other adaptive traits in bacteria. Obtaining a robust
method for plasmid classification is necessary to better understand the genetics and
epidemiology of many pathogens. Until now, plasmid classification systems focused on
specific traits, which limited their precision and universality. The definition of plasmid
taxonomic units (PTUs), based on average nucleotide identity metrics, allows the generation …
resistance, virulence determinants and other adaptive traits in bacteria. Obtaining a robust
method for plasmid classification is necessary to better understand the genetics and
epidemiology of many pathogens. Until now, plasmid classification systems focused on
specific traits, which limited their precision and universality. The definition of plasmid
taxonomic units (PTUs), based on average nucleotide identity metrics, allows the generation …