Fractional flow reserve derived from coronary computed tomography enables anatomical
and haemodynamic assessment of coronary artery disease in a single non-invasive test. Its
diagnostic performance has been established against invasive fractional flow reserve in
multi-centre trials, and a growing body of evidence has demonstrated its utility in predicting
clinical outcomes. The purpose of this article is to describe the physiological principles,
review its diagnostic performance, and describe the role of this technology in a real world …