[HTML][HTML] Cadmium effects on the retina of adult Danio rerio

B Avallone, R Crispino, R Cerciello, P Simoniello… - Comptes rendus …, 2015 - Elsevier
B Avallone, R Crispino, R Cerciello, P Simoniello, R Panzuto, CM Motta
Comptes rendus biologies, 2015Elsevier
The aim of this work is to describe the effects of cadmium pollution on the vision of adult
zebrafish, Danio rerio. Retinal morpho-cytological alterations were investigated by light and
electron microscopy, while the functionality of cadmium-exposed retinae was assessed by re-
illumination behavioral tests with white or colored light. Our results demonstrate that
cadmium toxicity causes significant degeneration and loss of organization at both macro and
microscopic levels. These alterations impair functional responses particularly through an …
Abstract
The aim of this work is to describe the effects of cadmium pollution on the vision of adult zebrafish, Danio rerio. Retinal morpho-cytological alterations were investigated by light and electron microscopy, while the functionality of cadmium-exposed retinae was assessed by re-illumination behavioral tests with white or colored light. Our results demonstrate that cadmium toxicity causes significant degeneration and loss of organization at both macro and microscopic levels. These alterations impair functional responses particularly through an increase in light sensitivity. Metallothioneins were not seen to be up-regulated, while the recovery of visual acuity is due to a regenerative process by Müller cells.
Elsevier
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