Cancer chemopreventive diterpenes from Salvia corrugata
E Giacomelli, S Bertrand, A Nievergelt, V Zwick… - Phytochemistry, 2013 - Elsevier
Abstract NMR and NP-HPLC-UV profiling of the exudate of Salvia corrugata revealed that its
secondary metabolite composition was largely dominated by α-hydroxy-β-isopropyl-
benzoquinone diterpenoids. Among them, four diterpenes not described previously were
isolated and identified as fruticulin C (3), 7α-methoxy-19-acetoxy-royleanone (4), 7α, 19-
diacetoxy-royleanone (5), and 7-dehydroxy-conacytone (7). In addition, the known
diterpenes fruticulin A (1), demethyl-fruticulin A (2) and 7α-O-methyl-conacytone (6) were …
secondary metabolite composition was largely dominated by α-hydroxy-β-isopropyl-
benzoquinone diterpenoids. Among them, four diterpenes not described previously were
isolated and identified as fruticulin C (3), 7α-methoxy-19-acetoxy-royleanone (4), 7α, 19-
diacetoxy-royleanone (5), and 7-dehydroxy-conacytone (7). In addition, the known
diterpenes fruticulin A (1), demethyl-fruticulin A (2) and 7α-O-methyl-conacytone (6) were …
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