Candidate Anti‐COVID‐19 Medicinal Plants from Ethiopia: A Review of Plants Traditionally Used to Treat Viral Diseases

D Tegen, K Dessie, D Damtie - … ‐Based Complementary and …, 2021 - Wiley Online Library
D Tegen, K Dessie, D Damtie
Evidence‐Based Complementary and Alternative Medicine, 2021Wiley Online Library
Background. Emerging viral infections are among the major global public health concerns.
The pandemic COVID‐19 is a contagious respiratory and vascular disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). There are no medicines
that can treat SARS‐CoV‐2 except the vaccines. Therefore, searching for plant‐originated
therapeutics for the treatment of COVID‐19 is required. Consequently, reviewing medicinal
plants used to treat different viral infections is mandatory. This review article aims to review …
Background. Emerging viral infections are among the major global public health concerns. The pandemic COVID‐19 is a contagious respiratory and vascular disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). There are no medicines that can treat SARS‐CoV‐2 except the vaccines. Therefore, searching for plant‐originated therapeutics for the treatment of COVID‐19 is required. Consequently, reviewing medicinal plants used to treat different viral infections is mandatory. This review article aims to review the ethnobotanical knowledge of medicinal plants traditionally used to treat different viral diseases by the Ethiopian people and suggests those plants as candidates to fight COVID‐19. Methods. Articles written in English were searched from online public databases using searching terms like “Traditional Medicine,” “Ethnobotanical study,” “Active components,” “Antiviral activities,” and “Ethiopia.” Ethnobotanical data were analyzed using the Excel statistical software program. Result. From the 46 articles reviewed, a total of 111 plant species were claimed to treat viral infections. Fifty‐six (50.4%) of the plant species had reported to have antiviral active components that are promising to treat COVID‐19. Lycorine, gingerol shogaol, resveratrol, rhoifolin, oleanolic acid, kaempferol, rosmarinic acid, almond oil, ursolic acid, hederagenin, nigellidine, α‐hederin, apigenin, nobiletin, tangeretin, chalcone, hesperidin, epigallocatechin gallate, allicin, diallyl trisulfide, ajoene, aloenin, artemisinin, glucobrassicin, curcumin, piperine, flavonoids, anthraquinone, hydroxychloroquine, and jensenone were some of them. Conclusion. The Ethiopian traditional knowledge applies a lot of medicinal plants to treat different viral infections. Reports of the chemical components of many of them confirm that they can be promising to fight COVID‐19.
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