Carbon black and titanium dioxide nanoparticles elicit distinct apoptotic pathways in bronchial epithelial cells

S Hussain, LCJ Thomassen, I Ferecatu… - Particle and fibre …, 2010 - Springer
Background Increasing environmental and occupational exposures to nanoparticles (NPs)
warrant deeper insight into the toxicological mechanisms induced by these materials. The
present study was designed to characterize the cell death induced by carbon black (CB) and
titanium dioxide (TiO 2) NPs in bronchial epithelial cells (16HBE14o-cell line and primary
cells) and to investigate the implicated molecular pathways. Results Detailed time course
studies revealed that both CB (13 nm) and TiO 2 (15 nm) NP exposed cells exhibit typical …

[PDF][PDF] Research Carbon black and titanium dioxide nanoparticles elicit distinct apoptotic pathways in bronchial epithelial cells

S Hussain, LCJ Thomassen, I Ferecatu… - 2010 - particleandfibretoxicology …
Background: Increasing environmental and occupational exposures to nanoparticles (NPs)
warrant deeper insight into the toxicological mechanisms induced by these materials. The
present study was designed to characterize the cell death induced by carbon black (CB) and
titanium dioxide (TiO2) NPs in bronchial epithelial cells (16HBE14o-cell line and primary
cells) and to investigate the implicated molecular pathways. Results: Detailed time course
studies revealed that both CB (13 nm) and TiO2 (15 nm) NP exposed cells exhibit typical …
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