Background and purpose: Carbon monoxide (CO) is a potent modulator of a wide variety of
physiological processes, including sensory signal transduction. Many afferent sensory
pathways are dependent upon purinergic neurotransmission, but direct modulation of the
P2X purinoceptors by this important, endogenously produced gas has never been
investigated. Experimental approach: Whole‐cell patch‐clamp experiments were used to
measure ATP‐elicited currents in human embryonic kidney 293 cells heterologously …

Carbon monoxide is a rapid modulator of recombinant and native P2X2 ligand-gated ion channels
[Abstract] -ORCA … Carbon monoxide is a rapid modulator of recombinant and native P2X2
ligand-gated ion channels [Abstract] … Carbon monoxide is a rapid modulator of recombinant
and native P2X2 ligand-gated ion channels [Abstract]. Purinergic Signalling 4 (S1) , p. 26. …