… angiogenic imbalance, accentuated by pre-eclampsia. Mice that lack cardiac PGC-1α, a
powerful regulator of angiogenesis, … Importantly, the PPCM is entirely rescued by pro-angiogenic …

… In line with recent studies postulating that angiogenic imbalance leads to acute PPCM, the
results of our study demonstrate for the first time that women recovering from PPCM may still …

… , which can lead to delayed diagnosis. In a … the angiogenic balance in the peripartum phase,
thereby promoting metabolic shortage in the heart, with potential negative effects on cardiac …

… is peripartum cardiomyopathy (PPCM). PPCM most commonly presents with acute heart failure
in the weeks following pregnancy, leading to … angiogenesis in the plasma and myocardial …

… dysfunction in the peripartum phase (which encompasses the period leading up to the end
… of cardiovascular disease in general. Deletion of PGC1α results in angiogenic imbalance 20 …

… shows that angiogenic imbalance in the heart during the peri-partum period may lead to …
-hit” combination of 1) systemic anti-angiogenic signals during late pregnancy, and 2) a host …

… Cardiovascular disease has become the leading cause of … Analysis of changes in maternal
circulating angiogenic factors … Circulating antiangiogenic factors and myocardial dysfunction …

… to both hypertensive and cardiac disorders via angiogenic imbalance may explain common
… antiangiogenic factors during the later pregnancy (stage 2). The angiogenic imbalance leads …

… perinatal care may account for this regional disparity. … leads to overexpression of cathepsin
D, which cleaves prolactin into its 16-kDa active form, thereby enhancing the antiangiogenic …

… Heart failure due to preeclampsia and eclampsia is characterized by left ventricular
hypertrophy and diastolic dysfunction. Unlike PPCM, left ventricular systolic function is generally …