Catalytic one-pot synthesis of trisubstituted allenes from terminal alkynes and ketones
An efficient one-pot synthesis of trisubstituted allenes from readily available terminal alkynes
and ketones is realized. A wide range of trisubstituted allenes may be synthesized efficiently
via this method. Preliminary mechanistic studies revealed that CuI and Ti (OEt) 4 are in
charge of the formation of propargylic amine, while ZnBr2 is responsible for the
transformation from propargylic amine to allene.
and ketones is realized. A wide range of trisubstituted allenes may be synthesized efficiently
via this method. Preliminary mechanistic studies revealed that CuI and Ti (OEt) 4 are in
charge of the formation of propargylic amine, while ZnBr2 is responsible for the
transformation from propargylic amine to allene.
An efficient one-pot synthesis of trisubstituted allenes from readily available terminal alkynes and ketones is realized. A wide range of trisubstituted allenes may be synthesized efficiently via this method. Preliminary mechanistic studies revealed that CuI and Ti(OEt)4 are in charge of the formation of propargylic amine, while ZnBr2 is responsible for the transformation from propargylic amine to allene.
ACS Publications以上显示的是最相近的搜索结果。 查看全部搜索结果