Cell metabolism is closely related to the host immunity in many respects. We herein briefly
summarized the recent progress on the roles of cellular metabolism in T-cell development,
homeostasis, differentiation and functions. Relatively quiescent naïve T cells only require
energy for survival and migration, and they mainly metabolize glucose to carbon dioxide
through oxidative phosphorylation. However, activated T cells engage in robust cell
proliferation, produce of a range of effector molecules and migrate through peripheral …

Cell metabolism is closely related to the host immunity in many respects. We herein briefly
summarized the recent progress on the roles of cellular metabolism in T-cell development,
homeostasis, differentiation and functions. Relatively quiescent naıve T cells only require
energy for survival and migration, and they mainly metabolize glucose to carbon dioxide
through oxidative phosphorylation. However, activated T cells engage in robust cell
proliferation, produce of a range of effector molecules and migrate through peripheral …