Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity

E Dec, J Clement, K Cheng, GM Church, MB Fossel… - Geroscience, 2023 - Springer
Claims surrounding exceptional longevity are sometimes disputed or dismissed for lack of
credible evidence. Here, we present three DNA methylation-based age estimators
(epigenetic clocks) for verifying age claims of centenarians. The three centenarian clocks
were developed based on n= 7039 blood and saliva samples from individuals older than 40,
including n= 184 samples from centenarians, 122 samples from semi-supercentenarians
(aged 105+), and 25 samples from supercentenarians (aged 110+). The oldest individual …

[引用][C] Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity. Geroscience. 2023

E Dec, J Clement, K Cheng
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