There have been many recent advances in distributed systems that provide stronger semantics for geo-replicated data stores like those underlying Facebook. These research systems provide a range of consistency models and transactional abilities while demonstrating good performance and scalability on experimental workloads. At Facebook we are excited by these lines of research, but fundamental and operational challenges currently make it infeasible to incorporate these advances into deployed systems. This paper describes some of these challenges with the hope that future advances will address them.