Charge driven fragmentation of nucleobases

J De Vries, R Hoekstra, R Morgenstern, T Schlathölter - Physical review letters, 2003 - APS
… ionization energy induces substantial fragmentation. The direct … of nucleobases with the
electric field of a slow highly charged … HCI-induced ionization and fragmentation of diatomic and …

More than charged base loss—revisiting the fragmentation of highly charged oligonucleotides

A Nyakas, RP Eberle, SR Stucki… - Journal of The American …, 2014 - ACS Publications
… the fragmentation behavior of highly charged oligodeoxynucleotides (ODNs) comprising up
to 15 nucleobases … states, which led to the conclusion that the main driving force for charged

Charge driven fragmentation of biologically relevant molecules

T Schlathölter, R Hoekstra, R Morgenstern - International Journal of Mass …, 2004 - Elsevier
nucleobases uracil and thymine by means of coincidence time-of-flight spectrometry. Our
measurements clearly show that fragment … 5–25) with nucleobases we extended our studies to …

Radical Cascade Dissociation Pathways to Unusual Nucleobase Cation Radicals

V Zima, Y Liu, F Tureček - Journal of the American Society for …, 2022 - ACS Publications
… in which nucleobase oxidation by Cu II was driven by collision… Charging is achieved by
electrospray ionization to protonate … 325) and the next generation fragment ion by loss of acetone …

Ion‐Induced Biomolecular Radiation Damage: From Isolated Nucleobases to Nucleobase Clusters

T Schlathölter, F Alvarado, S Bari, A Lecointre… - …, 2006 - Wiley Online Library
charged ions with the isolated nucleobases uracil, thymine, and adenine, and with their clusters.
Already for small clusters, fragmentation … induced fragmentation of isolated nucleobases

Charged nucleobases and their potential for RNA catalysis

JL Wilcox, AK Ahluwalia… - Accounts of chemical …, 2011 - ACS Publications
… Indeed, charged nucleobases have been implicated in RNA catalysis … nucleobase catalysis
and the complications involved in developing these mechanisms. We also consider driving

Gas-phase fragmentation of oligonucleotide ions

J Wu, SA McLuckey - International Journal of Mass Spectrometry, 2004 - Elsevier
driven by the interaction between the 5′-end nucleobase and the 2′-H proton of the sugar
moiety, as demonstrated previously, accounting for a charge driven fragmentation process. …

Charge-state-dependent collision-induced dissociation behaviors of RNA oligonucleotides via high-resolution mass spectrometry

RX Sun, MQ Zuo, JS Zhang… - Journal of the American …, 2023 - ACS Publications
… , numerous fragmentation pathways have been identified, including various sequence-determining
ions resulting from backbone cleavage, neutral or charged nucleobase losses from …

DFT study of the fragmentation mechanism of uracil RNA base

LS Arani, P Mignon, H Abdoul-Carime… - Physical Chemistry …, 2012 - pubs.rsc.org
… keV multi-charge carbon ions. It is shown that the dissociation of the nucleobase, regardless
… particles, leads to similar fragments with the same mass–charge ratio (m/z). Particularly, the …

State-dependent fragmentation of protonated uracil and uridine

M Pitzer, C Ozga, C Kustner-Wetekam… - The Journal of …, 2019 - ACS Publications
… a charged precursor, which is then photoexcited by a UV laser (see, eg, the reviews (13,14)).
Protonated nucleobases … , thus driving the excess energy into fragmentation of the weakest …