The essential oil of Haplophyllum tuberculatum was prepared by hydrodistillation of the
fresh flowering aerial parts of the plant collected from Saudi Arabia. The oil was
subsequently analyzed by GC and GC-MS. Thirty seven compounds, accounting for 96.4%
of the oil composition were identified. The major components were trans-p-menth-2-en-1-ol
(19.2%), cis-p-menth-2-en-1-ol (13.2%), myrcene (10.1%), δ-3-carene (8.8%), β-
phellandrene (6.9%), limonene (6.6%) and cis-piperitol (6.4%). The antimicrobial activity of …

… Antimicrobial activity of the essential oil was determined using the broth microdilution
method against various human pathogens, where a relatively low inhibitory range was
observed (MIC 1 mg/mL). Furthermore, the … The essential oil showed no antifungal activity
at 80 and 160 µg/spot concentrations compared to commercial antifungal standards. The oil
was also investigated for its insecticidal and repellent activity against Aedes aegypti. The …