Chiral peptide nucleic acid monomers (PNAM) with modified backbones
AR Katritzky, T Narindoshvili - Organic & biomolecular chemistry, 2008 - pubs.rsc.org
AR Katritzky, T Narindoshvili
Organic & biomolecular chemistry, 2008•pubs.rsc.orgConvenient high yielding syntheses of optically pure PNAMs comprising L-or D-serine, L-
lysine and L-arginine units linked to thymine or Cbz-cytosine are described. Simple workup
and inexpensive reagents are employed and free amino acids are used as coupling
components.
lysine and L-arginine units linked to thymine or Cbz-cytosine are described. Simple workup
and inexpensive reagents are employed and free amino acids are used as coupling
components.
Convenient high yielding syntheses of optically pure PNAMs comprising L- or D-serine, L-lysine and L-arginine units linked to thymine or Cbz-cytosine are described. Simple workup and inexpensive reagents are employed and free amino acids are used as coupling components.
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