Cholesterol trafficking and distribution

DB Iaea, FR Maxfield - Essays in biochemistry, 2015 - portlandpress.com
trafficking of cholesterol. However, several aspects of the mechanisms involved in regulating
trafficking and distribution of cholesterol remain … in cholesterol distribution and the trafficking

Cellular cholesterol trafficking and compartmentalization

E Ikonen - Nature reviews Molecular cell biology, 2008 - nature.com
… The lateral and transbilayer distribution of cholesterol. Several … of cholesterol trafficking,
the information obtained should help to develop improved strategies for controlling cholesterol-…

Intracellular cholesterol trafficking and impact in neurodegeneration

F Arenas, C Garcia-Ruiz… - Frontiers in molecular …, 2017 - frontiersin.org
… in the distribution of cholesterol in intracellular … -cholesterol levels is necessary to ensure
correct mtDNA function. Thus, disruption in mitochondrial cholesterol trafficking and distribution

Routes and mechanisms of post‐endosomal cholesterol trafficking: a story that never ends

J Luo, L Jiang, H Yang, BL Song - Traffic, 2017 - Wiley Online Library
… transport, and further work is needed to unveil how various routes are regulated and
integrated to maintain proper cholesterol distribution and homeostasis in eukaryotic cells. …

Intracellular cholesterol transport

FR Maxfield, D Wüstner - The Journal of clinical …, 2002 - Am Soc Clin Investig
… The correct intracellular distribution of cholesterol among cellular membranes is essential
traffic. Intracellular trafficking plays a major role in the proper disposition of internalized …

Role of cholesterol in SNARE-mediated trafficking on intracellular membranes

C Enrich, C Rentero, A Hierro… - Journal of cell …, 2015 - journals.biologists.com
… Here, we will first summarize our current knowledge of cholesterol homeostasis, in particular
the cellular distribution of low-density lipoprotein (LDL), which is linked to events that are …

Intracellular cholesterol trafficking

E Ikonen, VM Olkkonen - Cold Spring Harbor …, 2023 - cshperspectives.cshlp.org
… Our understanding of key cholesterol trafficking routes in mammalian cells has traditionally
… Yet, studying cholesterol trafficking remains challenging, since cells seem to be able to …

Interactions between metabolism and intracellular distribution of cholesterol and sphingomyelin

ND Ridgway - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2000 - Elsevier
… of cholesterol synthesis and trafficking, SM regulates the capacity of membranes to absorb
cholesterol … Constitutive PM to ER cholesterol trafficking is also ATP-independent and likely …

Intracellular cholesterol transport

RE Soccio, JL Breslow - Arteriosclerosis, thrombosis, and vascular …, 2004 - Am Heart Assoc
cholesterol distribution. Vesicles may have sorting mechanisms to exclude or incorporate …
However, because cholesterol trafficking and oxysterol generation clearly influence each …

Lipid and cholesterol trafficking in NPC

S Mukherjee, FR Maxfield - Biochimica et biophysica acta (BBA)-Molecular …, 2004 - Elsevier
… is a gross alteration in its distribution. In the NPC neurons, cholesterol in fact accumulated
in the LSOs in the cell bodies, whereas cholesterol was depleted from endosomal organelles …