[HTML][HTML] Chronic phase chronic myeloid leukemia patients with low OCT-1 activity randomized to high-dose imatinib achieve better responses and have lower failure …

DL White, J Radich, S Soverini, VA Saunders… - …, 2012 - ncbi.nlm.nih.gov
DL White, J Radich, S Soverini, VA Saunders, AK Frede, P Dang, D Cilloni, P Lin, L Mongay
haematologica, 2012ncbi.nlm.nih.gov
Background The functional activity of the organic cation transporter 1 (OCT-1) protein (OCT-
1 activity) is an excellent predictor of molecular response and progression-free survival in
patients with newly diagnosed chronic phase chronic myeloid leukemia treated with imatinib
as front-line therapy.
Abstract
Background
The functional activity of the organic cation transporter 1 (OCT-1) protein (OCT-1 activity) is an excellent predictor of molecular response and progression-free survival in patients with newly diagnosed chronic phase chronic myeloid leukemia treated with imatinib as front-line therapy.
ncbi.nlm.nih.gov
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