Chronopharmacokinetics of drugs in toxicological aspects: a short review for pharmacy practitioners
P Erkekoglu, T Baydar - Journal of research in pharmacy practice, 2012 - journals.lww.com
A rough 24-hour cycle driven endogenously in biochemical, physiological or behavioral
processes is called circadian rhythm. Chronobiology is the study of biological temporal
rhythms. For decades, we know that the biological rhythm and the drug metabolism are also
affected from daylight and chronopharmacology became recognized by scientists in the
early 1970s. Its lateral branch chronocopharmacokinetics is the study of rhythmic,
predictable-in-time differences in the pharmacokinetics of drugs. Chronopharmacokinetic …
processes is called circadian rhythm. Chronobiology is the study of biological temporal
rhythms. For decades, we know that the biological rhythm and the drug metabolism are also
affected from daylight and chronopharmacology became recognized by scientists in the
early 1970s. Its lateral branch chronocopharmacokinetics is the study of rhythmic,
predictable-in-time differences in the pharmacokinetics of drugs. Chronopharmacokinetic …
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