energies, which in turn can be addressed by chemical modifications. This article focuses
exclusively on the use of 'click'-chemistry for NP-surface modification, also putting a major
focus on the application of the resulting NPs in bio-and nanoscience. As 'click'-chemistry is a
universal method to link reaction partners in high efficiency, solvent insensitivity and at
moderate reaction conditions, its use for engineering NP surfaces has become widespread …