The goal of this study was to evaluate the clinical sonographic evaluation of postmenopausal bleeding (PMB) followed by diagnostic and/or therapeutic hysteroscopy and guided biopsy in Jordanian hospitals. A retrospective multi-centric study was performed in hospitals in Al-Karak and Amman from 2014–2016. The study recruited 189 cases to evaluate the aetiology of postmenopausal bleeding. Atrophic endometrium was observed as a major cause of postmenopausal bleeding according to histopathology. The cases were also distributed according to parity in which nulliparous patients were observed. Hysteroscopy was observed to be effective for the diagnosis of postmenopausal bleeding. There is a need to assess more approaches for the diagnosis of postmenopausal bleeding among women.