Clinical experience of modified diffusion‐weighted imaging protocol for lesion detection in transient global amnesia: An 8‐year large‐scale clinical study
J Kim, Y Kwon, Y Yang, IM Jang… - Journal of …, 2014 - Wiley Online Library
Journal of Neuroimaging, 2014•Wiley Online Library
ABSTRACT BACKGROUND AND PURPOSE The detection rate of typical transient global
amnesia (TGA) lesions on diffusion‐weighted imaging (DWI) can be improved, up to 85%
with optimal DWI parameters and imaging time. There is limited evidence that these findings
are similar to those observed in large‐scale consecutive patients with TGA in clinical
practice. METHODS Patients with clinically diagnosed TGA underwent magnetic resonance
imaging studies, consecutively, with three sets of DWI parameters (standard clinical DWI …
amnesia (TGA) lesions on diffusion‐weighted imaging (DWI) can be improved, up to 85%
with optimal DWI parameters and imaging time. There is limited evidence that these findings
are similar to those observed in large‐scale consecutive patients with TGA in clinical
practice. METHODS Patients with clinically diagnosed TGA underwent magnetic resonance
imaging studies, consecutively, with three sets of DWI parameters (standard clinical DWI …
BACKGROUND AND PURPOSE
The detection rate of typical transient global amnesia (TGA) lesions on diffusion‐weighted imaging (DWI) can be improved, up to 85% with optimal DWI parameters and imaging time. There is limited evidence that these findings are similar to those observed in large‐scale consecutive patients with TGA in clinical practice.
METHODS
Patients with clinically diagnosed TGA underwent magnetic resonance imaging studies, consecutively, with three sets of DWI parameters (standard clinical DWI protocols, the TGA DWI protocol I and the TGA DWI protocol II) in which the resolution, slice thickness, and the time interval between symptom onset of DWI were varied over an 8‐year period.
RESULTS
TGA lesion detection rates were up to 88% with a modified TGA DWI protocol. The lesion detection rate was the highest using TGA DWI protocol I, with b = 3,000 s/mm2, a slice thickness of 3 mm, and performed on the third day after symptom onset, and TGA DWI protocol II, with b = 2,000 s/mm2 and a slice thickness of 2 mm.
CONCLUSIONS
A modified TGA DWI protocols for detecting TGA lesions are useful in large‐scale clinical practice for confirming the diagnosis of TGA patients with clinical findings.
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