Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia

H Cavé, J van der Werff Ten Bosch… - … England Journal of …, 1998 - Mass Medical Soc
childhood acute lymphoblastic leukemia (ALL), the risk of relapse remains about 30 percent.
Studies have shown that the presence or absence of residual disease, … of residual leukemic

Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology …

MJ Borowitz, M Devidas, SP Hunger… - Blood, The Journal …, 2008 - ashpublications.org
Minimal residual disease (MRD) is an important predictor of relapse in acute lymphoblastic
leukemia … The Children's Oncology Group studied the prognostic impact of MRD measured by …

Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia after first relapse

E Coustan-Smith, A Gajjar, N Hijiya, BI Razzouk… - Leukemia, 2004 - nature.com
Clinical importance of minimal residual disease in childhood acute lymphoblastic leukemia.
… prior to stem cell transplant for childhood acute lymphoblastic leukaemia. Br J Haematol …

Clinical significance of low levels of minimal residual disease at the end of remission induction therapy in childhood acute lymphoblastic leukemia

P Stow, L Key, X Chen, Q Pan, GA Neale… - Blood, The Journal …, 2010 - ashpublications.org
… predicts relapse in acute lymphoblastic leukemia (ALL). We examined the clinical significance
of levels below the usual threshold value for MRD positivity (0.01%) in 455 children with B-…

Clinical importance of minimal residual disease in childhood acute lymphoblastic leukemia

E Coustan-Smith, J Sancho… - Blood, The Journal …, 2000 - ashpublications.org
… detecting one leukemic cell in 10 4 normal cells, we prospectively … minimal residual disease
(MRD) in 195 children with newly diagnosed acute lymphoblastic leukemia (ALL) in clinical

Prognostic significance and modalities of flow cytometric minimal residual disease detection in childhood acute lymphoblastic leukemia

MN Dworzak, G Fröschl, D Printz… - Blood, The Journal …, 2002 - ashpublications.org
… Reducing the need for a diversified investigative setup should add to the clinical
significance of FC also by augmenting its economic efficiency. We suggest that a methodologic …

Minimal residual disease in acute lymphoblastic leukemia

D Campana - Hematology 2010, the American Society of …, 2010 - ashpublications.org
acute lymphoblastic leukemia (ALL), treatment response is increasingly evaluated with minimal
residual disease (… The clinical significance of MRD has been conclusively demonstrated …

Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia

, … Study Group for Adult Acute Lymphoblastic Leukemia - Blood, 2006 - ashpublications.org
… Adult patients with acute lymphoblastic leukemia (ALL) who are stratified into the standard-…
ALL, we evaluated the predictive value of minimal residual disease (MRD) and prospectively …

Clinical significance of novel subtypes of acute lymphoblastic leukemia in the context of minimal residual disease–directed therapy

S Jeha, J Choi, KG Roberts, D Pei, E Coustan-Smith… - Blood cancer …, 2021 - AACR
clinical significance of recently identified subtypes of acute lymphoblastic leukemia (ALL) in
598 children treated with minimal residual disease (MRD)–directed therapy. Among the 16 B-…

Role of minimal residual disease monitoring in adult and pediatric acute lymphoblastic leukemia

D Campana - Hematology/oncology clinics of North America, 2009 - Elsevier
minimal residual disease (MRD) can determine the response to treatment in patients with
acute lymphoblastic leukemia (… The clinical significance of MRD, detected by flow cytometry or …