Clinical signs, lethal dose and histopathological lesions in grass carp, Ctenopharyngodon idella experimentally infected with Edwardsiella tarda
An experiment was conducted to study the lethal dose (LD 50-96h) and histopathological
changes occurring in several organs of grass carp challenged with different concentrations
of Edwardsiella tarda. The healthy grass carps were challenged with the bacterial
suspension of 10 6, 10 7, 10 8, 10 9 and 10 10 CFU ml− 1. The study demonstrated that the
lethal dose (LD 50-96h) of E. tarda for grass carp is 1.3× 10 9 CFU ml− 1. The infected fish
showed abnormal swimming behavior, slower movements, skin necrosis, hemorrhages, and …
changes occurring in several organs of grass carp challenged with different concentrations
of Edwardsiella tarda. The healthy grass carps were challenged with the bacterial
suspension of 10 6, 10 7, 10 8, 10 9 and 10 10 CFU ml− 1. The study demonstrated that the
lethal dose (LD 50-96h) of E. tarda for grass carp is 1.3× 10 9 CFU ml− 1. The infected fish
showed abnormal swimming behavior, slower movements, skin necrosis, hemorrhages, and …
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