Clinical validation of SPECT attenuation correction using x-ray computed tomography–derived attenuation maps: multicenter clinical trial with angiographic correlation

Y Masood, YH Liu, G DePuey, R Taillefer… - Journal of nuclear …, 2005 - Elsevier
BACKGROUND: Nonuniform attenuation artifacts cause suboptimal specificity of stress
single photon emission computed tomography (SPECT) myocardial perfusion images. In
phantoms, normal subjects, and patients suspected of having coronary artery disease
(CAD), we evaluated a new hybrid attenuation correction (AC) system that combines x-ray
computed tomography (CT) with conventional stress SPECT imaging. METHODS AND
RESULTS: The effect of CT-based AC was evaluated in phantoms by assessing …
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