Clonidine compounding error: bradycardia and sedation in a pediatric patient
AF Barbuto, MM Burns - The Journal of Emergency Medicine, 2020 - Elsevier
Background Clonidine is a centrally-acting α-2 agonist used in the treatment of hypertension
and attention-deficit/hyperactivity disorder, among other off-label uses. In overdose, it can
cause sedation, bradycardia, and hypotension. Clonidine can be compounded as a liquid
formula for patients who are unable to take pills, however, this can add to the risk of dosing
errors. Case Report A 12-year-old boy diagnosed with autism, prescribed buspirone and
clonidine, presented to the emergency department for altered mental status. His examination …
and attention-deficit/hyperactivity disorder, among other off-label uses. In overdose, it can
cause sedation, bradycardia, and hypotension. Clonidine can be compounded as a liquid
formula for patients who are unable to take pills, however, this can add to the risk of dosing
errors. Case Report A 12-year-old boy diagnosed with autism, prescribed buspirone and
clonidine, presented to the emergency department for altered mental status. His examination …
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