Cloning and distribution of myosin 3B in the mouse retina: differential distribution in cone outer segments
C Katti, JS Dalal, AC Dosé, B Burnside… - Experimental eye …, 2009 - Elsevier
Class III myosins are important for the function and survival of photoreceptors and ciliary hair
cells. Although vertebrates possess two class III myosin genes, myo3A and myo3B, recent
studies have focused on Myo3A because mutations in the human gene are implicated in
progressive hearing loss. Myo3B may compensate for defects in Myo3A, yet little is known
about its distribution and function. This study focuses on Myo3B expression in the mouse
retina. We cloned two variants of myo3B from mouse retina and determined that they are …
cells. Although vertebrates possess two class III myosin genes, myo3A and myo3B, recent
studies have focused on Myo3A because mutations in the human gene are implicated in
progressive hearing loss. Myo3B may compensate for defects in Myo3A, yet little is known
about its distribution and function. This study focuses on Myo3B expression in the mouse
retina. We cloned two variants of myo3B from mouse retina and determined that they are …
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