and biocompatible polymer, polyvinylpyrrolidone, was studied using sub-and supercritical
carbon dioxide (CO 2) technology, namely in the present work by pressurized anti-solvent
(PAS). A full design was used to evaluate the effect of pressure (90, 130 and 170 bar) and
temperature (20, 32 and 45 ºC) on the PAS process and the characteristics of the particles
formed by it. The particles obtained from the best PAS conditions were submitted to in vitro …