Co-transplantation of xenogeneic bone marrow–derived Mesenchymal stem cells alleviates rejection of pancreatic islets in non-obese diabetic mice

C Corradi-Perini, TM Santos, NOS Camara… - Transplantation …, 2017 - Elsevier
Bone marrow–mesenchymal stem cells (BM-MSCs) have generated a great perspective in
the field of regenerative medicine, and also in the treatment of inflammatory and
autoimmune diseases in the past decade due to their immunomodulatory and anti-
inflammatory properties. Here, we investigated the effect of xenogeneic BM-MSCs and
pancreatic islets co-transplantation obtained from Wistar rats in preventing rejection or
inducing tolerance to islet transplantation in non-obese diabetic mice. Non-obese diabetic …
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