Home-based rehabilitation is an essential step to maximize the recovery of patients during their rehabilitation programs. Experts, between scheduled sessions, recommend home-based rehabilitation exercises. However, there is a lack of motivation for patients to perform these repetitive tasks. Serious games have been used recently as a solution for this problem. These games also help improve the patient motivation problem, but most of them do not include cognitive aspects. In this paper, we propose a serious gaming system, for cognitive and functional rehabilitation, implemented using a system of systems approach. The overall system integrates inertial sensors and Kinect cameras to estimate the kinematic data of the patient, and a dance pad to interact with the game.