Cohort Profile Update: Southall and Brent Revisited (SABRE) study: a UK population-based comparison of cardiovascular disease and diabetes in people of …

S Jones, T Tillin, C Park, S Williams… - International journal …, 2020 - academic.oup.com
S Jones, T Tillin, C Park, S Williams, A Rapala, L Al Saikhan, SV Eastwood, M Richards…
International journal of epidemiology, 2020academic.oup.com
Advance Access Publication Date: 13 October 2020 Cohort Profile from middle-to old-age.
This will further the aetiological understanding of heart failure, exercise intolerance and
cognitive decline. Advances in genetic, epigenetic and metabolomics analyses will also
enhance understanding of the mechanisms underlying ethnic differences in cardiometabolic
disease prevalence. This will ultimately lead to improved preventive strategies and
treatments at different stages of life. To address previous limitations of the SABRE study, in …
Advance Access Publication Date: 13 October 2020 Cohort Profile from middle-to old-age. This will further the aetiological understanding of heart failure, exercise intolerance and cognitive decline. Advances in genetic, epigenetic and metabolomics analyses will also enhance understanding of the mechanisms underlying ethnic differences in cardiometabolic disease prevalence. This will ultimately lead to improved preventive strategies and treatments at different stages of life.
To address previous limitations of the SABRE study, in the current sweep we recruited partners of index participants with the objective of recruiting additional women and a new intake of African Caribbeans, who were, by design, recruited in lower numbers at baseline. The objective of this was to increase the power of cross-sectional analyses investigating ethnic and sex differences.
Oxford University Press
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