In this study, the authors confirm and expand previous findings (M. Anastasi, R. G. Sawyer, & P. J. Pinciaro, 1999; J. E. Lewis & R. M. Malow, 1997) concerning college students' knowledge and perceptions about HIV/AIDS. Although students are knowledgeable about HIV/AIDS, they have little personal concern about becoming infected and do not take appropriate safe sex precautions. Findings of the present study show that gender, ethnic background, and knowing someone infected by HIV/AIDS influence students' level of concern about infection. In addition, older students and those who know someone infected by HIV/AIDS are more likely to have been tested. Results are compared with national surveys of other age groups, and the authors suggest specific intervention strategies for college students.