Objective Assess the association between combined hormonal contraceptives (CHC) use
and musculoskeletal tissue pathophysiology, injuries or conditions. Design Systematic
review with semiquantitative analyses and certainty of evidence assessment, guided by the
Grading of Recommendations Assessment, Development and Evaluation approach. Data
Sources MEDLINE, EMBASE, CENTRAL, SPORTDiscus, CINAHL searched from inception
to April 2022. Eligibility Intervention and cohort studies that assessed the association …

Introduction Half of young women start combined hormonal contraceptive (CHC) use for non-
contraceptive reasons including 'controlling'their menstrual cycle to prevent injuries. These
decisions should be evidence-based. This study assessed the association between CHC
use and musculoskeletal tissue pathophysiology, injuries, or conditions. Materials and
Methods After protocol registration, five databases were searched to 04–2022. Intervention
and cohort studies assessing the association between new or ongoing use of CHC and …