[HTML][HTML] Comparative genomics reveals conserved positioning of essential genomic clusters in highly rearranged Thermococcales chromosomes
M Cossu, V Da Cunha, C Toffano-Nioche, P Forterre… - Biochimie, 2015 - Elsevier
The genomes of the 21 completely sequenced Thermococcales display a characteristic high
level of rearrangements. As a result, the prediction of their origin and termination of
replication on the sole basis of chromosomal DNA composition or skew is inoperative. Using
a different approach based on biologically relevant sequences, we were able to determine
oriC position in all 21 genomes. The position of dif, the site where chromosome dimers are
resolved before DNA segregation could be predicted in 19 genomes. Computation of the …
level of rearrangements. As a result, the prediction of their origin and termination of
replication on the sole basis of chromosomal DNA composition or skew is inoperative. Using
a different approach based on biologically relevant sequences, we were able to determine
oriC position in all 21 genomes. The position of dif, the site where chromosome dimers are
resolved before DNA segregation could be predicted in 19 genomes. Computation of the …
以上显示的是最相近的搜索结果。 查看全部搜索结果