Comparative glycopattern analysis of mucins in the Brunner's glands of the guinea-pig and the house mouse (Rodentia)

G Scillitani, D Mentino - Acta Histochemica, 2015 - Elsevier
The mucins secreted by the Brunner's glands and the duodenal goblet cells of the Guinea-
pig and the house mouse were compared by conventional and FITC-conjugated lectin
histochemistry. Methylation/saponification and sialidase digestion were performed prior to
lectin binding to detect the residues subterminal to sulfated groups and sialic acid,
respectively. In the Guinea-pig the Brunner's glands produce class-III stable
sulfosialomucins. Sialic acid is mostly 2, 6-linked to galactose or to N-acetylgalactosamine …
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