Comparative physiology of nociception and pain

LU Sneddon - Physiology, 2017 - journals.physiology.org
Physiology, 2017journals.physiology.org
The study of diverse animal groups allows us to discern the evolution of the neurobiology of
nociception. Nociception functions as an important alarm system alerting the individual to
potential and actual tissue damage. All animals possess nociceptors, and, in some animal
groups, it has been demonstrated that there are consistent physiological mechanisms
underpinning the nociceptive system. This review considers the comparative biology of
nociception and pain from an evolutionary perspective.
Abstract
The study of diverse animal groups allows us to discern the evolution of the neurobiology of nociception. Nociception functions as an important alarm system alerting the individual to potential and actual tissue damage. All animals possess nociceptors, and, in some animal groups, it has been demonstrated that there are consistent physiological mechanisms underpinning the nociceptive system. This review considers the comparative biology of nociception and pain from an evolutionary perspective.
American Physiological Society
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