Background: Chronic inflammatory diseases (CIDs) are considered risk enhancing factors
for coronary heart disease (CHD). However, sparse data exist regarding relative CHD risks
across CIDs. Objective: Determine relative differences in CHD risk across multiple CIDs:
psoriasis, rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), human
immunodeficiency virus (HIV), systemic sclerosis (SSc), and inflammatory bowel disease
(IBD). Methods: The cohort included patients with CIDs and controls without CID in an urban …

Introduction: Inflammation plays an important role in the pathogenesis of coronary heart
disease (CHD). Chronic inflammatory diseases (CIDs) may serve as models to provide
insights into the relationships between immune dysfunction, inflammation, and CHD. To
investigate this further, we analyzed the risk of incident CHD across different CIDs. Methods:
We created a cohort of individuals with CIDs and non-CID controls (frequency-matched on
demographics and CHD risk factors), free of baseline CHD, receiving regular outpatient care …