Comparison of dutasteride and finasteride for treating benign prostatic hyperplasia: the Enlarged Prostate International Comparator Study (EPICS)

JC Nickel, P Gilling, TL Tammela, B Morrill… - BJU …, 2011 - Wiley Online Library
Study Type–Therapy (RCT) Level of Evidence 1b What's known on the subject? and What
does the study add? Both dutasteride and finasteride inhibit type 2 5α‐reductase, the
dominant form of 5α‐reductase in benign prostatic tissue, making these effective treatments
for BPH. In comparison with finasteride, dutasteride has a longer half‐life and leads to a
greater and more consistent suppression of serum and intraprostatic DHT. EPICS is
currently the only prospective, randomized, double‐blind study of finasteride vs dutasteride …

[引用][C] Re: comparison of dutasteride and finasteride for treating benign prostatic hyperplasia: the Enlarged Prostate International Comparator Study (EPICS).

SA Kaplan - The Journal of Urology, 2011 - europepmc.org
… Re: comparison of dutasteride and finasteride for treating benign prostatic hyperplasia:
the Enlarged Prostate International Comparator Study (EPICS). … [Combined treatment of
BPS with tamsulosin and finasteride : Literature review and prescription data]. … To arrive
at the top five similar articles we use a word-weighted algorithm to compare words from the
Title and Abstract of each citation. …
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