Defective interfering passages of Sindbis virus: chemical composition, biological activity, and mode of interference

B Weiss, S Schlesinger - Journal of Virology, 1973 - Am Soc Microbiol
… 'ic RNA synthesis and which, upon co-infection with standard virus, inhibit RNA synthesis.
The RNA isolated from these defective virions was identical in molecular weight to infectious …

Inhibiting eukaryotic transcription. Which compound to choose? How to evaluate its activity? Which compound to choose? How to evaluate its activity?

O Bensaude - Transcription, 2011 - Taylor & Francis
… is active at very low concentrations (IC 50 = 109 nM for inhibition of RNA synthesis in HeLa
… The length of the transcription unit and its DNA sequence composition are determinant.…

RNA interference: biology, mechanism, and applications

N Agrawal, PVN Dasaradhi, A Mohmmed… - Microbiology and …, 2003 - Am Soc Microbiol
… function of micro-RNAs resemble RNAi activities to a large … Specific inhibition of gene
expression by these siRNAs has … or a change in the composition of an siRNP ahead of the …

Basis of actinomycin action, I. DNA binding and inhibition of RNA-polymerase synthetic reactions by actinomycin

IH Goldberg, M Rabinowitz… - Proceedings of the …, 1962 - National Acad Sciences
activity also influence, in a parallel way, its binding to DNA and its inhibition of the RNA
effect of actinomycin in that the base composition of DNA primers may influence the extent …

RNA interference and small interfering RNAs

T Tuschl - Chembiochem, 2001 - Wiley Online Library
RNA helicase activity may also be evoked in other steps of … in the composition of an siRNP
must occur prior to target RNA … the nuclease that cleaves dsRNA also cleaves the target RNA. …

[HTML][HTML] Inhibition of respiratory RNA viruses by a composition of ionophoric polyphenols with metal ions

T Kreiser, D Zaguri, S Sachdeva, R Zamostiano… - Pharmaceuticals, 2022 - mdpi.com
RNA viruses in vitro. Importantly, as the compounds are known for their diverse antiviral
activities [32,60,61], we infer that viral inhibition … viruses, particularly RNA viruses associated with …

Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication

X Lai, Y Yu, W Xian, F Ye, X Ju, Y Luo, H Dong… - Iscience, 2022 - cell.com
… to remove most proteins without antiviral activity. After precipitation with different … for their
inhibition of viral infection. We found that most of the ingredients with antiviral activity were …

[HTML][HTML] Composition of naturally occurring compounds decreases activity of Omicron and SARS-CoV-2 RdRp complex

A Goc, M Rath, A Niedzwiecki - European Journal of Microbiology …, 2022 - akjournals.com
inhibit viral RNA replication is by replacing ATP in the newly synthesized viral RNA strand
and, as such, terminate the RNA … nucleoside analogs that inhibited RNA synthesis in other …

Casein kinase type II is involved in the inhibition by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole of specific RNA polymerase II transcription.

R Zandomeni, MC Zandomeni, D Shugar… - Journal of Biological …, 1986 - ASBMB
… We report here the subunit composition of a DRB-… inhibits RNA polymerase I1 transcription,
also inhibits specific in vitro RNA I1 polymerase transcription and casein kinase I1 activity. In …

Influence of the Composition of Cationic Liposomes on the Performance of Cargo Immunostimulatory RNA

A Bishani, DM Makarova, EV Shmendel, MA Maslov… - Pharmaceutics, 2023 - mdpi.com
… of liposomal compositions on the immunostimulatory activity of isRNA in vivo, the activity of
… the use of the PKR protein inhibitor 2-aminopurine or hairpin RNA targeting the PKR gene …