Context-dependent differences in miR-10b breast oncogenesis can be targeted for the prevention and arrest of lymph node metastasis

MV Yigit, SK Ghosh, M Kumar, V Petkova, A Kavishwar… - Oncogene, 2013 - nature.com
… growth raising the possibility of a context-dependent variation in miR-10b breast oncogenesis.
… In the present study, we focused on targeting miR-10b, with the goal of alleviating breast

A comprehensive review on oncogenic miRNAs in breast cancer

M Nurzadeh, M Naemi, S Sheikh Hasani - Journal of Genetics, 2021 - Springer
… In this review, we try to discuss the expression pattern of oncogenic miRNAs and their target
MiR-10b has a great association with invasive and metastatic breast cancer cells as shown …

[HTML][HTML] Dual Roles of miR-10a-5p and miR-10b-5p as Tumor Suppressors and Oncogenes in Diverse Cancers

R Singh, SE Ha, TY Yu, S Ro - International Journal of Molecular …, 2025 - mdpi.com
… underscore their complex and context-dependent regulatory … miR-10b-5p as a critical
therapeutic target and its oncogenic … underscore miR-10b-5p as a pivotal oncogene in breast

Role of miR-10b in breast cancer metastasis

L Ma - Breast cancer research, 2010 - Springer
… transcription factor with context-dependent oncogenic or tumor-… as a direct target of miR-10b
in esophageal squamous cell … of miR-10b has been demonstrated in different xenograft …

[HTML][HTML] The fundamental role of miR-10b in metastatic cancer

P Sheedy, Z Medarova - American journal of cancer research, 2018 - ncbi.nlm.nih.gov
… of miR-10b in the paired liver metastasis in comparison to the … However, while mostly
oncogenic, miR-10b could also be … own work focused on miR-10b as a therapeutic target in breast

miRNA-based therapeutics in breast cancer: a systematic review

AM Grimaldi, M Salvatore, M Incoronato - Frontiers in oncology, 2021 - frontiersin.org
… the therapeutic silencing of miR-10b inhibited metastasis in a … receiving end of the miR-10b
pathway is the proto-oncogene c-Jun (… have specific context-dependent roles. These are very …

[PDF][PDF] Dual Roles of miR-10a and miR-10b as Tumor Suppressors and Oncogenes in Diverse Cancers

R Singh, SE Ha, TY Yu, S Ro - 2024 - preprints.org
… , highlighting their context-dependent functionality [16,24,25]. … miR-10b as a critical therapeutic
target and its oncogenic … underscore miR-10b as a pivotal oncogene in breast cancer, …

Context dependent roles of microRNA-150-5p in normal mammary gland development and breast cancer

RE Heinz - 2016 - search.proquest.com
… dedicated to my mom, whose battle with breast cancer inspired … transcript can be targeted
by an assortment of different … to predict target sites can produce widely different results, …

The Role, Significance, and Association of MicroRNA-10a/b in Physiology of Cancer

KM Elgeshy, AHA Abdel Wahab - MicroRNA, 2022 - ingentaconnect.com
… significantly inhibit miRNA-10b and reverse its oncogenic function in breast cancer both in
vitro … Context-dependent differences in miR-10b breast oncogenesis can be targeted for the …

Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties

A Halim, N Al-Qadi, E Kenyon, KN Conner… - …, 2024 - pmc.ncbi.nlm.nih.gov
… mechanisms of miR-10b inhibition, we next sought to identify and compare the biological …
expression of genes associated with the proto-oncogene transcription factor c-Jun [12]. As c-…