[HTML][HTML] Controlled assembly of biocompatible metallic nanoaggregates using a small molecule crosslinker

D Van Haute, JM Longmate… - … materials (Deerfield Beach …, 2015 - ncbi.nlm.nih.gov
Advanced materials (Deerfield Beach, Fla.), 2015ncbi.nlm.nih.gov
By introducing a capping step and controlling reaction parameters, the assembly of metallic
nanoparticle aggregates can be achieved using a small molecule crosslinker. Aggregates
can be assembled from particles of varied size and composition and the size of the
aggregates can be systematically adjusted. Following cell uptake of 60 nm aggregates, the
aggregates are stable and non-toxic to macrophage cells up to 55mM Au.
Abstract
By introducing a capping step and controlling reaction parameters, the assembly of metallic nanoparticle aggregates can be achieved using a small molecule crosslinker. Aggregates can be assembled from particles of varied size and composition and the size of the aggregates can be systematically adjusted. Following cell uptake of 60 nm aggregates, the aggregates are stable and non-toxic to macrophage cells up to 55mM Au.
ncbi.nlm.nih.gov
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