Correlation of phylogenetic clade diversification and in vitro infectivity differences among Cosmopolitan genotype strains of Chikungunya virus
R Abraham, A Manakkadan, P Mudaliar… - Infection, genetics and …, 2016 - Elsevier
Cosmopolitan genotypes of Chikungunya virus caused the large-scale febrile disease
outbreaks in the last decade in Asian and African continents. Molecular analyses of these
strains had revealed significant genetic diversification and occurrence of novel mosquito-
adaptive mutations. In the present study we looked into whether the genetic diversification
has implications in the infectivity phenotype. A detailed sequence and phylogenetic
analyses of these virus strains of Indian Ocean lineage from Kerala, South India from the …
outbreaks in the last decade in Asian and African continents. Molecular analyses of these
strains had revealed significant genetic diversification and occurrence of novel mosquito-
adaptive mutations. In the present study we looked into whether the genetic diversification
has implications in the infectivity phenotype. A detailed sequence and phylogenetic
analyses of these virus strains of Indian Ocean lineage from Kerala, South India from the …
Correlation of phylogenetic clade diversification and in vitro infectivity differences among Cosmopolitan genotype strains of Chikungunya virus.
RA Rachy Abraham, AM Anoop Manakkadan… - 2016 - cabidigitallibrary.org
Cosmopolitan genotypes of Chikungunya virus caused the large-scale febrile disease
outbreaks in the last decade in Asian and African continents. Molecular analyses of these
strains had revealed significant genetic diversification and occurrence of novel mosquito-
adaptive mutations. In the present study we looked into whether the genetic diversification
has implications in the infectivity phenotype. A detailed sequence and phylogenetic
analyses of these virus strains of Indian Ocean lineage from Kerala, South India from the …
outbreaks in the last decade in Asian and African continents. Molecular analyses of these
strains had revealed significant genetic diversification and occurrence of novel mosquito-
adaptive mutations. In the present study we looked into whether the genetic diversification
has implications in the infectivity phenotype. A detailed sequence and phylogenetic
analyses of these virus strains of Indian Ocean lineage from Kerala, South India from the …
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