This work constructs an evaluation index system and quantitatively explores the coupling coordination relationship between the tourism development system and the medical services system in China. Results show that the degree of coupling coordination between the tourism development system and the medical services system showed a good upward trend in China during the period 2012–2019. However, the relationship was barely balanced, with tourism development lagging. The overall layout shows a spatial pattern of “high in the north and low in the south, high in the east and low in the west.” The degree of coupling coordination tends to be randomly distributed from clustered distribution, and the cold–hot spots show a spatial development pattern of “cold in the northwest and hot in the southeast” as time passes. The power of government to regulate has always been an important mechanism affecting the degree of coupling coordination. The study aims to provide reference for the rationalization of medical tourism layout and sustainable development.