CpG islands: features and distribution in the genomes of vertebrates
B Aïssani, G Bernardi - Gene, 1991 - Elsevier
We have investigated the distribution of unmethylated CpG islands in vertebrate genomes
fractionated according to their base composition. Genomes from warm-blooded vertebrates
(man, mouse and chicken) are characterized by abundant CpG islands, whose frequency
increases in DNA fractions of increasing% of guanine+ cytosine;% G+ C (GC), in parallel
with the distribution of genes and CpG doublets. Small, yet significant, differences in the
distribution of CpG islands were found in the three genomes. In contrast, genomes from cold …
fractionated according to their base composition. Genomes from warm-blooded vertebrates
(man, mouse and chicken) are characterized by abundant CpG islands, whose frequency
increases in DNA fractions of increasing% of guanine+ cytosine;% G+ C (GC), in parallel
with the distribution of genes and CpG doublets. Small, yet significant, differences in the
distribution of CpG islands were found in the three genomes. In contrast, genomes from cold …
[引用][C] CpG islands: features and distribution in the genomes of vertebrates
BA ssani, G Bernardi - Gene, 1991 - Elsevier Science
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