过去一年中添加的文章,按日期排序

Abstract B028: Deep mutational scanning of SMARCB1 identifies missense mutants that destabilize SWI/SNF complex stability and diminish remodeling activity

G Cooper, B Lee, W Kim, E Salas, Y Su, V Chen… - Cancer …, 2024 - aacrjournals.org
22 天前 - … domain, the intrinsically disordered region, and the RPT2 domain. Following our
high-throughput study, we then focused on two highly enriched residues predicted to closely …

[PDF][PDF] Correlation between Protein Disorder and Post Translational Modifications in Resistance Protein of Plants

SA Urmee, R Hasan, J Alam - J biotech bioinform, 2024 - opastpublishers.com
23 天前 - … in plant proteins which play critical role … predictor in this study because its scores
were closer to the experimentally derived scores of intrinsic disorder for PDBdeposited protein

Streamlining NMR Chemical Shift Predictions for Intrinsically Disordered Proteins: Design of Ensembles with Dimensionality Reduction and Clustering

MJ Bakker, A Gaffour, M Juhás, V Zapletal… - Journal of Chemical …, 2024 - ACS Publications
53 天前 - disordered proteins (IDPs), making a significant leap forward in the field of protein
analysis/… This investigation critically assessed different rapid CS predictors, both neural …

PredIDR: Accurate prediction of protein intrinsic disorder regions using deep convolutional neural network

KS Han, SJ Yun, CS Kim, CP Ri, A Del Conte… - bioRxiv, 2024 - biorxiv.org
64 天前 - … to predict intrinsic disorder from protein sequences were … by the Critical Assessment
of protein Intrinsic Disorder (… prediction of intrinsically disordered regions in proteins, …

[HTML][HTML] The Vitreous Proteome and its Association with Intrinsic Protein Disorder

M Antonietti, DJT Gonzalez… - … & Visual Science, 2024 - iovs.arvojournals.org
102 天前 - analysis using PONDR, we predicted 334 proteins (26.9%) as highly disordered,
852 proteins (68.8%) as moderate disorder … the presence of intrinsic disorder and LLPS …

Evaluating Effects of Cellular Environment on Protein Folding

A Kruglikov - 2024 - ruor.uottawa.ca
106 天前 - predictions and manipulations of protein function. … , each addressing critical aspects
of protein structure and cellular … significance of intrinsically disordered proteins in bacterial …

Engineering computational single-cell and CRISPR-based functional genomics tools to study dynamic gene regulation in hematopoietic development and disease

ME Vinyard - 2024 - dash.harvard.edu
137 天前 - … We study the model’s ability to predict the effects of in … to highlight functionally critical
domains of the LSD1 protein. … surprising role for the intrinsically disordered terminal tail of …

flDPnn2: Accurate and Fast Predictor of Intrinsic Disorder in Proteins

K Wang, G Hu, S Basu, L Kurgan - Journal of Molecular Biology, 2024 - Elsevier
142 天前 - … The disorder predictors are periodically … Critical Assessment of protein Intrinsic
Disorder prediction (CAID) experiments. The recently completed CAID2 experiment assessed

[HTML][HTML] Exploring Intrinsic Disorder in Human Synucleins and Associated Proteins

SR Venati, VN Uversky - International Journal of Molecular Sciences, 2024 - mdpi.com
156 天前 - predicted to be highly disordered proteins, indicating that their intrinsically disordered
… , these observations highlight the critical importance of the intrinsic disorder of human …

[HTML][HTML] Functions of the Bloom Syndrome Helicase N-terminal Intrinsically Disordered Region

CC Bereda, EB Dewey, MA Nasr, J Sekelsky - bioRxiv, 2024 - ncbi.nlm.nih.gov
165 天前 - … 2 ) plot predicting the ordered and intrinsically disordered … 2 (CR1 and CR2) are
predicted to be mostly disordered (>0.5). (B… We conclude that the CR2 region is more critical for …