Critical discovery and synthesis of novel antibacterial and resistance-modifying agents inspired by plant phytochemical defense mechanisms

SSM Soliman, BQ Saeed, SA Elseginy… - Chemico-Biological …, 2021 - Elsevier
Antimicrobial resistance is at increasing risk worldwide since it is threatening the ability to
control common infectious diseases, resulting in prolonged illness, disability, and death.
Herein, we inspired by the effective plant phytochemical mechanisms evolved to overcome
microbial pathogenesis and evolved resistance. Cuminaldehyde is previously reported as
the main antibacterial component in Calligonum comosum essential oil. The toxicity of
cuminaldehyde limits its medical application for human use. On the other hand, compared to …

Critical discovery and synthesis of novel antibacterial and resistance-modifying agents inspired by plant phytochemical defense mechanisms

RHA Badawi - Elsevier, 2020 - publications.zu.edu.eg
Antimicrobial resistance is at increasing risk worldwide since it is threatening the ability to
control common infectious diseases, resulting in prolonged illness, disability, and death.
Herein, we inspired by the effective plant phytochemical mechanisms evolved to overcome
microbial pathogenesis and evolved resistance. Cuminaldehyde is previously reported as
the main antibacterial component in Calligonum comosum essential oil. The toxicity of
cuminaldehyde limits its medical application for human use. On the other hand, compared to …
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